Aging and Sex, DNA Repair in
97
A p53-p66Shc signalling pathway controls
intracellular redox status, levels of oxidation-
damaged DNA and oxidative stress-induced
apoptosis,
Oncogene
21
, 3872–3878.
Tuo, J.,
Muftuoglu, M.,
Chen, C.,
Jaruga, P.,
Selzer, R.R., Brosh, R.M. Jr., Rodriguez, H.,
Dizdaroglu, M., Bohr, V.A. (2001) The Cock-
ayne syndrome group B gene product is
involved in general genome base excision
repair of 8-hydroxyguanine in DNA,
J. Biol.
Chem.
276
, 45772–45779.
Tyner,
S.D.,
Venkatachalam,
S.,
Choi,
J.,
Jones, S., Ghebranious, N., Igelmann, H., Lu,
X., Soron, G., Cooper, B., Brayton, C., Hee
Park, S., Thompson, T., Karsenty, G., Bradley,
A., Donehower, L.A. (2002) p53 mutant mice
that display early ageing-associated pheno-
types,
Nature
415
, 45–53.
van Brabant, A.J., Ye, T., Sanz, M., Ger-
man, J.L. Jr.,
Ellis,
N.A.,
Holloman, W.K.
(2000) Binding and melting of D-loops by
the Bloom syndrome helicase,
Biochemistry
39
,
14617–14625.
van Steeg, H., Mullenders, L.H.F., Vijg, J. (2000)
Mutagenesis and carcinogenesis in nucleotide
excision repair-de±cient XPA knock out mice,
Mutat. Res.
450
, 167–180.
Vikhanskaya, F.,
Marchini, S.,
Marabese, M.,
Galliera, E., Broggini, M. (2001) p73
α
over-
expression is associated with resistance to
treatment with DNA-damaging agents in a
human ovarian cancer cell line,
Cancer Res.
61
,
935–938.
Vogel, H., Lim, D.S., Karsenty, G., Finegold, M.,
Hasty, P. (1999) Deletion of Ku86 causes early
onset of senescence in mice,
Proc. Natl. Acad.
Sci. U.S.A.
96
, 10770–10775.
Wakayama, T., Perry, A.C.F., Zucotti, M., John-
son, K.R., Yanagimachi, R. (1998) Full-term
development of mice from enucleated oocytes
injected with cumulus cell nuclei,
Nature
394
,
369–374.
Wang, X., Peterson, C.A., Zheng, H., Nairn, R.S.,
Legerski, R.J., Li, L. (2001) Involvement of
nucleotide excision repair in a recombination-
independent and error-prone pathway of DNA
interstrand cross-link repair,
Mol. Cell. Biol.
21
, 713–720.
Wang, Y.,
Cortez, D.,
Yazdi, P.,
Neff, N.,
Elledge, S.J., Qin, J. (2002) BASC, a super
complex
of
BRCA1-associated
proteins
involved in the recognition and repair of
aberrant DNA structures,
Genes Dev.
14
,
927–939.
Wedekind, C., Furi, S. (1997) Body odor prefer-
ences in men and women: do they aim for
speci±c MHC combinations or simply het-
erozygosity?
Proc. R. Soc. London B Biol. Sci.
264
, 1471–1479.
Weeda, G., Donker, I., de Wit, J., Morreau, H.,
Janssens, R.,
Vissers, C.J.,
Nigg, A.,
van
Steeg, H., Bootsma, D., Hoeijmakers, J.H.J.
(1997) Disruption of mouse
ERCC1
results in
a novel repair syndrome with growth failure,
nuclear abnormalities and senescence,
Curr.
Biol.
7
, 427–439.
Wijnhoven, S.W., Kool, H.J., van Oostrom, C.T.,
Beems, R.B.,
Mullenders, L.H.,
van
Zee-
land, A.A., van der Horst, G.T., Vrieling, H.,
van Steeg, H. (2000) The relationship be-
tween benzo[a]pyrene-induced mutagenesis
and carcinogenesis in repair-de±cient Cock-
ayne syndrome group B mice,
Cancer Res.
60
,
5681–5687.
Williams, M.D.,
Van
Remmen, H.,
Con-
rad, C.C., Huang, T.T., Epstein, C.J., Richard-
son, A. (1998) Increased oxidative damage is
correlated to altered mitochondrial function
in heterozygous manganese superoxide dis-
mutase knockout mice,
J. Biol. Chem.
272
,
28510–28515.
Willis, J.H. (1999) Inbreeding load, average
dominance and mutation rate for mildly
deleterious alleles in
Nimulus guttatus
,
Genetics
153
, 1885–1898.
Wilmut, I., Schnieke, A.E., McWhir, J., Kind,
A.J., Campbell, K.H.S. (1997) Viable offspring
derived from fetal and adult mammalian cells,
Nature
385
, 810–813.
Wilson, E.O. (1978)
On Human Nature
,Harvard
University Press: Cambridge, MA.
Wu, L., Davies, S.L., Levitt, N.C., Hickson, I.D.
(2001) Potential role for the BLM helicase
in recombinational repair via a conserved
interaction with RAD51,
J. Biol. Chem.
276
,
19375–19381.
Yang, Q., Zhang, R., Wang, X.W., Spillare, E.A.,
Linke, S.P., Subramanian, D., Grif±th, J.D.,
Li, J.L., Hickson, I.D., Shen, J.C., Loeb, L.A.,
Mazur, S.J., Appella, E., Brosh R.M. Jr., Kar-
makar, P., Bohr, V., Harris, C.C. (2002) The
processing of Holliday junctions by BLM and
WRN helicases is regulated by p53,
J. Biol.
Chem.
277
, 31980–31987.
Yannone, S.M.,
Roy, S.,
Chan, D.W.,
Mur-
phy, M.B., Huang, S., Campisi, J., Chen, D.J.
previous page 97 Encyclopedia of Molecular Cell Biology and Molecular Medicine read online next page 99 Encyclopedia of Molecular Cell Biology and Molecular Medicine read online Home Toggle text on/off