Cancer Stem Cells
239
Miller, C.L., Eaves, C.J. (1997) Expansion in vitro
of adult murine hematopoietic stem cells with
transplantable lympho-myeloid reconstituting
ability,
Proc. Natl. Acad. Sci. U.S.A.
94
(25),
13648–13653.
Miyamoto, T., Weissman, I.L., Akashi, K. (2000)
AML1/ETO-expressing
nonleukemic
stem
cells in acute myelogenous leukemia with 8;21
chromosomal translocation,
Proc. Natl. Acad.
Sci. U.S.A.
97
(13), 7521–7526.
Morrison, S., Hemmati, H., Wandycz, A., Weiss-
man, I. (1995) The puriFcation and charac-
terization of fetal liver hematopoietic stem
cells,
P
r
o
c
.N
a
t
l
.A
c
a
d
.S
c
i
.U
.
S
.A
.
92
(22),
10302–10306.
Morrison, S.,
Perez, S.,
Qiao, Z.,
Verdi, J.,
Hicks, C.,
Weinmaster, G.,
Anderson, D.
(2000) Transient notch activation initiates
an irreversible switch from neurogenesis to
gliogenesis by neural crest stem cells,
Cell
101
,
499–510.
Morrison, S.J., Qian, D., Jerebek, L., Thiel, B.A.,
Park, I.-K., ±ord, P.S., Kiel, M.J., Schork, N.J.,
Weissman, I.L., Clarke, M.±. (2002) A genetic
determinant that speciFcally regulates the
frequency of hematopoietic stem cells,
J.
Immunol.
168
(2), 635–642.
Morrison, S.J.,
Shah, N.M.,
Anderson, D.J.
(1997) Regulatory mechanisms in stem cell
biology,
Cell
88
(3), 287–298.
Morrison, S.J.,
Uchida, N.,
Weissman, I.L.
(1995) The biology of hematopoietic stem cells,
Annu. Rev. Cell Dev. Biol
11
, 35–71.
Morrison, S.J., Weissman, I.L. (1994) The long-
term repopulating subset of hematopoietic
stem cells is deterministic and isolatable by
phenotype,
Immunity
1
(8), 661–673.
Mucenski, M.L., McLain, K., Kier, A.B., Swerd-
low,
S.H.,
Schreiner,
C.M.,
Miller, T.A.,
Pietryga, D.W.,
Scott, W.J.J.,
Potter, S.S.
(1991) A functional c-myb gene is required for
normal murine fetal hepatic hematopoiesis,
Cell
65
(4), 677–689.
Muller-Sieburg, C.E., Cho, R.H., Sieburg, H.B.,
Kupriyanov, S.,
Riblet, R.
(2000)
Genetic
control of hematopoietic stem cell frequency
in mice is mostly cell autonomous,
Blood
95
(7),
2446–2448.
Negrin, R.S.,, Atkinson, K., Leemhuis, T., Hana-
nia, E., Juttner, C., Tierney, K., Hu, W.W.,
Johnston,
L.J.,
Shizurn,
J.A.,
Stockerl-
Goldstein, K.E., Blume, K.G., Weissman, I.L.,
Bower, S., Baynes, R., Dansey, R., Karanes, C.,
Peters, W., Klein, J. (2000) Transplantation of
highly puriFed CD34
+
Thy-1
+
hematopoietic
stem cells in patients with metastatic breast
cancer,
Biol. Blood. Marrow Transplant.
6
(3),
262–271.
Negrin, R.S., Weissman, I.L. (1992) Hematopoi-
etic stem cells in normal and malignant states,
Marrow Transplant.
2
, 23–26.
Nowell, P.C.
(1986)
Mechanisms
of
tumor
progression,
Cancer Res.
46
(5), 2203–2207.
Nusse, R. (1992) The Wnt gene family in
tumorigenesis and in normal development,
J. Steroid Biochem. Mol. Biol.
43
((1–3)),9–12.
Nusse, R., Brown, A., Papkoff, J., Scambler, P.,
Schackleford, G.,
McMahon, A.,
Moon, R.,
Varmus, H. (1991) A new nomenclature for
int-1 and related genes: the Wnt gene family,
Cell
64
(2), 231.
Orkin, S.H.,
Morrison, S.J.
(2002)
Stem-cell
competition,
Nature
418
(6893), 25–27.
Osawa,
M.,
Hanada,
K.,
Hamada,
H.,
Nakauchi, H. (1996) Long-term lymphohe-
matopoietic reconstitution by a single CD34-
low/negative hematopoietic stem cell,
Science
273
(5272), 242–245.
Ozols, R.±., Willson, J.K., Weltz, M.D., Grot-
zinger, K.R., Myers, C.E., Young,, R.C. (1980)
Inhibition of human ovarian cancer colony
formation
by
adriamycin
and
its
major
metabolites,
Cancer Res.
40
(11), 4109–4112.
Park, C.H.,
Bergsagel, D.E.,
McCulloch, E.A.
(1971) Mouse myeloma tumor stem cells: a
primary cell culture assay,
J. Natl. Cancer Inst.
46
(2), 411–422.
Park, I.K.,
Clarke, M.±.
(2003)
Bmi-1
and
senescence regulation in stem cells,
JCI
(submitted).
Park, I.K., Qian, D., Kiel, M.J., Becker, M.W.,
Pihalja, M.,
Weissman, I.L.,
Morrison, S.J.,
Clarke, M.±. (2003) Bmi-1 is required for
the
maintenance
of
self-renewing
adult
hematopoietic stem cells,
Nature
423
(693),
302–305.
Peters, R., Leyvraz, S., Perey, L. (1998) Apoptotic
regulation
in
primitive
hematopoietic
precursors,
Blood
92
(6), 2041–2052.
Phillips, R.L., Reinhart, A.J., Van Zant, G. (1992)
Genetic control of murine hematopoietic stem
cell pool sizes and cycling kinetics,
Proc. Natl.
Acad. Sci. U.S.A.
89
(23), 11607–11611.
Platt, ±.M.,
Cebra-Thomas, J.A.,
Baum, C.M.,
Davie, J.M., McKearn, J.P. (1992) Monoclonal
antibodies speciFc for novel murine cell
surface markers deFne subpopulations of
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