214
Cancer of the Prostate: Molecular Genetics
in situ hybridization study,
Lab. Invest.
83
(5),
623–633.
Kantoff, P.W.,
Febbo, P.G.,
Giovannucci, E.,
et al. (1997) A polymorphism of the 5 alpha-
reductase
gene
and
its
association
with
prostate cancer: a case-control analysis,
Cancer
Epidemiol. Biomarkers Prev.
6
, 189–192.
Kim, I.Y., Ahn, H.J., Zelner, D.J., et al. (1996)
Loss of expression of transforming growth
factor beta type I and type II receptors
correlates with tumor grade in human prostate
cancer tissues,
Clin. Cancer Res.
2
, 1255–1261.
Kim, I.Y., Kim, J.H., Zelner, D.J., et al. (1996)
Transforming
growth
factor-beta-1
is
a
mediator of androgen-regulated growth arrest
in an androgen-responsive prostatic cancer cell
line, LNCaP,
Endocrinology
137
, 991–999.
Kim, I.Y.,
Zelner, D.J.,
Sensibar, J.A.,
et al.
(1996)
Modulation
of
sensitivity
to
transforming growth factor beta-1 (TGF-beta-
1) and the level of type II TGF-beta receptor in
LNCaP cells by dihydrotestosterone,
Exp. Cell
Res.
222
, 103–110.
Kito, H., Suzuki, H., Ichikawa, T., Sekita, N.,
Kamiya, N., Akakura, K., Igarashi, T., Naka-
yama, T., Watanabe, M., Harigaya, K., Ito, H.
(2001) Hypermethylation of the CD44 gene is
associated with progression and metastasis
of human prostate cancer,
Prostate
49
(2),
110–115.
Kleinerman, D.I., Troncoso, P., Lin, S.H., et al.
(1995) Consistent expression of an epithelial
cell
adhesion
molecule
(C-CAM)
during
human prostate development and loss of
expression in prostate cancer: implication as a
tumor suppressor,
Cancer Res.
5
, 1215–1220.
Koivisto, P.,
Kononen, J.,
Palmberg, C.,
et al.
(1997) Androgen receptor gene ampli±cation:
a possible molecular mechanism for androgen
deprivation therapy failure in prostate cancer,
Cancer Res.
57
, 314–319.
Konishi, N., Hiasa, Y., Tsuzuki, T., et al. (1996)
Detection of Rb, p16/cdkn2 and p15 (Ink4b)
gene alterations with immunohistochemical
studied in human prostate carcinomas,
Int. J.
Oncol.
8
, 107–112.
Konishi, N., Hiasa, Y., Tsuzuki, T., et al. (1997)
Comparison
of
ras activation
in prostate
carcinoma in Japanese and American men,
Prostate
30
, 53–7.
Kubota, Y.,
Fujinami, K.,
Uemura, H.,
et al.
(1995) Retinoblastoma gene mutations in
primary human prostate cancer,
Prostate
27
,
314–320.
Kuhn, E.J., Kurnot, R.A., Sesterhenn, I.A., et al.
(1993) Expression of the c–erbB-2 (HER-
2/neu)
oncoprotein
in
human
prostatic
carcinoma,
J. Urol.
150
, 1427–1433.
Kunimi, K., Amano, T., Uchibayashi, T. (1996)
Point mutation of the p53 gene is an infrequent
event in untreated prostate cancer,
Cancer
Detect. Prev.
20
, 218–222.
Kunimi, K., Bergerheim, U., Larsson, I.L., et al.
(1991)
Allelotyping
of
human
prostatic
adenocarcinoma,
Genomics
11
, 530–536.
Kyprianou, N. (1999) Activation of TGF-beta
signalling in human prostate cancer cells
suppresses tumorigenicity via deregulation of
cell cycle progression and induction of caspase-
1 mediated apoptosis: signi±cance in prostate
tumorigenesis,
Prostate Cancer Prostat. Dis.
2
(S3), S18.
Lacombe, L., Orlow, I., Reuter, V.E., et al. (1996)
Microsatellite instability and deletion analysis
of chromosome 10 in human cancer,
Int. J.
Cancer
69
, 110–113.
Lange, E.M., Chen, H., Brierley, K., et al. (1999)
Linkage
analysis
of
153
prostate
cancer
families
over
a
30-cM
region
containing
the putative susceptibility locus HPCX,
Clin.
Cancer Res.
5
, 4013–4020.
LaSpada, A.R., Wilson, E.M., Lubahn, D.B., et al.
(1991) Androgen receptor gene mutations in
X-linked spinal and bulbar muscular atrophy,
Nature
352
, 77–79.
Latil, A., Baron, J.-C., Cussenot, O., et al. (1994)
Genetic alterations in localized prostate cancer
identi±cation of a common region of deletion
on chromosome arm 18q,
Genes Chromosomes
Cancer
11
, 119–125.
Latil, A., Baron, J.-C., Cussenot, O., et al. (1994)
Oncogene ampli±cations in early-stage human
prostate
carcinomas,
Int.
J.
Cancer
59
,
637–638.
Latil, A., Cussenot, O., Fournier, G., Lidereau, R.
(1997) Infrequent allelic imbalance at the
major susceptibility HPC1 locus in sporadic
prostate tumors,
Int. J. Cancer
71
, 1118.
Latil, A., Lidereau, R. (1998) Genetic aspects of
prostate cancer,
Virchows Arch.
432
, 389–406.
Leach, F.S., Nicolaides, N.C., Papadopoulos, N.,
et al. (1993) Mutations of a mutS homolog in
hereditary nonpolyposis colorectal cancer,
Cell
75
, 1215–1225.
Lee, J.M., Bernstein, A. (1993) p53 mutations
increase resistance to ionizing radiation,
Proc.
Natl. Acad. Sci. U.S.A.
90
, 5742–5746.
previous page 888 Encyclopedia of Molecular Cell Biology and Molecular Medicine read online next page 890 Encyclopedia of Molecular Cell Biology and Molecular Medicine read online Home Toggle text on/off