133
Calcium Biochemistry
Joachim Krebs
Institute of Biochemistry, Swiss Federal Institute of Technology,
ETH-Hoenggerberg, Zuerich, Switzerland
1
Introduction
135
2C
a
2
+
Ligation
138
3
Calcium in the Extracellular Space
138
3.1
The Calcium Binding EGF-domain
139
3.2
The Extracellular Calcium Sensor
140
4
Signal Transduction Principles
140
4.1
General Properties
140
4.2
Calcium Oscillations in the Cell
141
4.3
Calcium and the Cell Cycle
142
4.4
Calcium and Apoptosis
142
5
Intracellular Calcium Binding Proteins
144
5.1
The EF-hand Protein Family
144
5.1.1
Calmodulin and its Targets
146
5.1.2
Neuronal Calcium Sensors
152
5.1.3
S100 Proteins
152
5.1.4
The Penta EF-hand Family
153
5.2
Non-EF-hand Ca
2
+
Binding Proteins
155
5.2.1
Annexins
155
5.2.2
Gelsolin
156
5.2.3
C
2
-domains
156
6
Systems Controlling Intracellular Ca
2
+
Concentration: Structural
and Functional Properties
156
6.1
Calcium Transport Systems of the Plasma Membrane
157
Encyclopedia of Molecular Cell Biology and Molecular Medicine, 2nd Edition
. Edited by Robert A. Meyers.
Copyright
2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
ISBN: 3-527-30544-0
previous page 807 Encyclopedia of Molecular Cell Biology and Molecular Medicine read online next page 809 Encyclopedia of Molecular Cell Biology and Molecular Medicine read online Home Toggle text on/off