30
Bioorganic Chemistry
7
Summary
We have briefly attempted to highlight the
principles of bioorganic chemistry that are
of general importance and of special inter-
est to the molecular biologist. In addition,
we have sought to illustrate these with
speciFc examples. Bioorganic chemistry
makes connections with a very broad range
of Felds, ranging from physical chemistry
to biochemistry. Obviously, we have just
scratched the surface of these topics in
this vital and rapidly expanding discipline.
See also
Bioinorganic Chemistry.
Bibliography
Books and Reviews
Benkovic, S.J. (1992) Catalytic antibodies,
Annu.
Rev. Biochem.
61
(29), 29–54.
Bertozzi, C.R., Kiessling, L.L. (2001) Chemical
glycobiology,
Science
291
(5512), 2357–2364.
Breslow, R.
(1998)
Biomimetic
chemistry:
a
frontier at the chemistry/biology interface,
Chem. Biol.
5
(2), R27, R28.
Breslow, R.,
Xu, R.
(1993)
Recognition
and
catalysis in nucleic acid chemistry,
Proc. Natl.
Acad.Sci.U.S.A.
90
(4), 1201–1217.
Dolle, R.
(2001)
Comprehensive
survey
of
combinatorial library synthesis: 2001,
J. Comb.
Chem.
3
(6), 477–517.
Dugas, H.
(1996)
Bioorganic
chemistry:
A
Chemical Approach to Enzyme Action, 3rd
edition.
Springer Advanced Texts in Chemistry
(Cantor, R.C.,
Ed.),
Springer-Verlag,
New
York.
±ersht, A. (1999)
Structure and Mechanism in
Protein Science: A Guide to Enzyme Catalysis
and Protein Folding
, W.H. ±reeman, New York.
±ields, G.B.
(1997)
Solid
Phase
Peptide
Synthesis,
Methods in Enzymology
, Vol. 289,
Academic Press, San Diego.
Hecht, S.M. (1996)
Bioorganic Chemistry: Nucleic
Acids.
Topics
in
Bioorganic
and
Biological
Chemistry
, Oxford University Press, New York.
Jung, G.
(1999)
Combinatorial
Chemistry:
Synthesis,
Analysis,
Screening
,W
i
l
e
y
-
V
C
H
,
Weinheim, Cambridge.
Muscate, A., Levinson, C.L., Kenyon, G.L. (1993)
Enzyme Inhibitors, in Encyclopedia of Chemical
Technology
, John Wiley & Sons, New York,
Vol. 9.
Nielsen, P.E., Egholm, M. (1999) An introduc-
tion to peptide nucleic acid,
Curr. Issues Mol.
Biol.
1
(1–2), 89–104.
Primary Literature
Anderson, J.C.,
Magliery, T.J.,
Schultz, P.G.
(2002) Exploring the limits of codon and
anticodon size,
Chem. Biol.
9
(2), 237–244.
Barsky, D.,
Kool, E.T.,
Colvin, M.E.
(1999)
Interaction and solvation energies of nonpolar
DNA
base
analogues
and
their
role
in
polymerase insertion Fdelity,
J. Biomol. Struct.
Dyn.
16
(6), 1119–1134.
Bertozzi, C.R., Kiessling, L.L. (2001) Chemical
glycobiology,
Science
291
(5512), 2357–2364.
Bishop, A.C., Ubersax, J.A., Petsch, D.T., Mathe-
os, D.P., Gray, N.S., Blethrow, J., Shimizu, E.,
Tsien, J.Z.,
Schultz,
P.G.,
Rose,
M.D.,
Wood, J.L., Morgan, D.O., Shokat, K.M. (2000)
A
chemical
switch
for
inhibitor-sensitive
alleles of any protein kinase,
Nature
407
(6802),
395–401.
Boger, D.L., Schmitt, H.W., ±ink, B.E., Hedrick,
M.P. (2001) Parallel synthesis and evaluation
of
132
(
+
)-1,2,9,9a-tetrahydrocyclopropa[c]
benz[e]indol-4-one (CBI) analogues of CC-
1065 and the duocarmycins deFning the
contribution of the DNA-binding domain,
J.
Org. Chem.
66
(20), 6654–6661.
Braasch, D.A.,
Corey, D.R.
(2002)
Novel
antisense and peptide nucleic acid strategies
for controlling gene expression,
Biochemistry
41
(14), 5403–5410.
Bruner,
S.D.,
Norman, D.P.,
Verdine, G.L.
(2000) Structural basis for recognition and
repair
of
the
endogenous
mutagen
8-
oxoguanine
in
DNA,
Nature
403
(6772),
859–866.
Chen, Z., Monia, B.P., Corey, D.R. (2002) Telom-
erase inhibition, telomere shortening, and
decreased cell proliferation by cell permeable
2
0
-o-methoxyethyl oligonucleotides,
J.
Med.
Chem.
45
(25), 5423–5425.
Chin, J.W.,
Schepartz, A.
(2001)
Concerted
evolution of structure
and function in a
previous page 704 Encyclopedia of Molecular Cell Biology and Molecular Medicine read online next page 706 Encyclopedia of Molecular Cell Biology and Molecular Medicine read online Home Toggle text on/off