659
Biological Regulation by Protein
Phosphorylation
Clay W. Scott
1
, Ratan V. Bhat
2
, and Gaochao Tian
1
1
Lead Discovery Department, AstraZeneca Pharmaceuticals LP,
Wilmington, DE, USA
2
Department of Bioscience, AstraZeneca R
&
DS
..
odert
..
alje, Huddinge, Sweden
1
Importance of Protein Phosphorylation in Biological Regulation
660
2
ClassiFcation and Properties of Protein Kinases
661
3
ClassiFcation and Properties of Phosphoprotein Phosphatases
665
4
Phosphorylation Cascades and Multisite Phosphorylations
667
5
Genetic and Pharmacological Modulation of Protein Phosphorylation
668
Bibliography
671
Books and Reviews
671
Primary Literature
671
Keywords
Protein Kinase
An enzyme that catalyzes the transfer of a phosphate group from a nucleoside
triphosphate (usually ATP) to an amino acid side chain of a substrate protein.
Phosphoprotein Phosphatase
An enzyme that removes phosphate groups from the amino acid side chains of
phosphorylated proteins.
Encyclopedia of Molecular Cell Biology and Molecular Medicine, 2nd Edition
. Edited by Robert A. Meyers.
Copyright
2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
ISBN: 3-527-30543-2
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