618
Biogenesis, Structure and Function of Lysosomes
Bibliography
630
Books and Reviews
630
Primary Literature
631
Keywords
Lysosome
An acidic organelle containing hydrolytic enzymes.
Vacuole
A large lysosome-like organelle found in yeast and plants.
Mannose 6-Phosphate Receptor
One of two proteins in mammalian cells that recognize lysosomal lumen proteins
tagged with mannose 6-phosphate.
Phosphoinositides
Lipids that act as second messengers and regulate vesicular trafFc.
Lysosomal Storage Disease
Defects in lysosomal enzyme activity or targeting that result in the lysosomal
accumulation of undigested materials.
Abbreviations
ALP
alkaline phosphatase
AP
adaptor protein
Aph
autophagosome
API
aminopeptidase I
Apg
autophagy
AR±
ADP-ribosylation factor
Cma
chaperone-mediated autophagy
COP
coatomer protein
CPY
carboxypeptidase Y
Cvt
cytoplasm-to-vacuole targeting
ER
endoplasmic reticulum
±BPase
fructose-1,6-bisphosphatase
±YVE
±ab1, YGLO23, Vps27, EEA1
GGA
Golgi-localizing, gamma adaptin ear homology domain, AR±-binding
Hsp70
heat shock protein of 70 kDa
Hsc70
the constitutively expressed hsp70
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