617
Biogenesis, Structure and
Function of Lysosomes
James Fred Dice
Department of Physiology, Tufts University School of Medicine,
136 Harrison Avenue, Boston, MA, USA
1
Lysosome Structure
620
2
Biogenesis of Mammalian Lysosomes
621
2.1
Proteins in the Lumen
621
2.2
Proteins in the Membrane
623
3
Biogenesis of the Yeast Vacuole
624
3.1
Proteins in the Lumen
624
3.2
Proteins in the Membrane
624
3.3
Vacuolar Inheritance
625
4
The Importance of Phosphoinositides in Lysosomal Biogenesis
625
5
Lysosomal Pathways of Proteolysis
626
5.1
Endocytosis
626
5.2
Exocytosis
627
5.3
Macroautophagy
627
5.4
Microautophagy
628
5.5
Vacuolar Import and Degradation Pathway
628
5.6
Chaperone-mediated Autophagy
629
6
Lysosomal Pathways of RNA Degradation
629
7
Lysosomal Storage Diseases
629
9
Conclusions
630
Encyclopedia of Molecular Cell Biology and Molecular Medicine, 2nd Edition
. Edited by Robert A. Meyers.
Copyright
2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
ISBN: 3-527-30543-2
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