481
Autoimmunity in Scleroderma
Yoshinao Muro
1
and Kenji Sugimoto
2
1
Nagoya Graduate University School of Medicine, Nagoya, Japan
2
Osaka Prefecture University, Sakai, Osaka, Japan
1
Scleroderma and Autoantibodies
483
1.1
Methods of Autoantibody Detection
483
1.2
Clinical Subsets of Scleroderma and Autoantibodies
483
1.3
Detection of Scleroderma Autoantibodies and Epitope Analysis
486
2
Centromere Antigens
486
2.1
Autoimmunity against Centromere Antigens
486
2.2
CENP-B and B-cell Epitopes
488
2.3
CENP-C and B-cell Epitopes
490
2.4
CENP-A and B-cell Epitopes
491
2.5
Centromere-associated Autoantigens
491
3
Topoisomerase I
492
3.1
Autoimmunity against Topoisomerase I
492
3.2
B-cell Epitope
492
3.3
T-cell Response
493
4
Scleroderma-associated Nucleolar Autoantigens
494
4.1
Fibrillarin
494
4.2
PM/Scl Antigen
494
5
Molecular Mimicry and Scleroderma Autoantigens
495
6
Apoptosis and Scleroderma Autoantigens
495
Encyclopedia of Molecular Cell Biology and Molecular Medicine, 2nd Edition
. Edited by Robert A. Meyers.
Copyright
2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
ISBN: 3-527-30543-2
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