353
Antigen Presenting Cells (APCs)
Harald Kropshofer and Anne B.Vogt
Roche Center for Medical Genomics, F. Hoffman-La Roche Ltd,
Basel, Switzerland
1
Antigen-specifc Immunity
357
2
Antigen Presenting Cells (APCs)
358
2.1
The Discovery of Langerhans
358
2.2
Professional APCs
358
2.3
Nonprofessional APCs
359
3
Antigens Presented by APCs
360
3.1
Antigen Types
360
3.2
Biochemical Nature of Antigens
361
3.3
Origin of Antigens
362
4
Antigen Entry Sites
362
4.1
APCs in the Skin
362
4.2
APCs in the Mucosa
363
4.3
APCs in the Gut
363
4.4
Antigen Uptake in the Respiratory Tract
364
5
Antigen Presenting Molecules
364
5.1
MHC Class I Molecules
364
5.2
MHC Class II Molecules
366
5.3
CD1 Molecules
366
6
Antigen Processing by APCs
367
6.1
MHC Class I Processing Pathways
368
6.1.1
Generation of Peptide Ligands
368
6.1.2
TAP
368
6.1.3
The MHC Class I Loading Complex
369
Encyclopedia of Molecular Cell Biology and Molecular Medicine, 2nd Edition
. Edited by Robert A. Meyers.
Copyright
2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
ISBN: 3-527-30543-2
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