The chemical processes that occur within a living organism in order to maintain life;
the interconnected sequences of mostly enzyme-catalyzed chemical reactions by which
a cell, tissue, organ, etc., sustains energy production, and synthesizes and breaks down
complex molecules.
Any of the large group of fats and fatlike compounds which occur in living organisms
and are characteristically soluble in certain organic solvents but only sparingly soluble
in water.
Fatty Acids
Long-chain aliphatic compounds that contain a carboxylic acid group.
Gene Expression
The process by which a gene’s coded information is converted into the structures
present and operating in the cell. Expressed genes include those that are transcribed
into mRNA and then translated into protein and those that are transcribed into RNA
but not translated into protein (e.g., transfer and ribosomal RNAs).
Transcription Factors
The DNA binding proteins that carry out the organic process whereby the DNA
sequence in a a gene is copied into mRNA.
Nuclear Receptors
Transcription factors that are activated by the binding of speciFc ligans that are usually
lipid soluble, such as fatty acids or steroids.
Adipose Tissue
Body tissue which is able to store high amounts of neutral fats.
The cell type found in adipose tissue that is specialized for storage of neutral lipids.
The adipocyte, or fat cell, is a unique, highly specialized cell whose primary function
is to provide a depot for storage of excess fat, derived mainly from the diet, which can
be mobilized and distributed to other tissues as dictated by the energetic demands
of the organism. Although long thought of as a simple passive storage depot for
dietary lipid, it is now clear that adipose tissuep
energy balance and not only stores and secretes lipid as needed, but also produces
hormonal signals that have multiple effects on energy metabolism in many tissue
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