Cytomegalovirus and Varicella–zoster Virus Vaccines
Single or Combined Vaccine Strategies in Human Clinical Trials
Animal Models Including Animal Homologues of Human CMV
Quantitation of Immune Responses in Immunized Animals
Books and Reviews
Natural or chemical substance that enhances antigen-stimulated antibody production
by B cells and/or activation of T cells.
Foreign substance that can stimulate a speci±c immune response, usually speci±c
antibody; speci±c determinants on the antigen that are bound by the antibody are
known as epitopes.
Replication-competent viral or bacterial vaccine; either an attenuated form of a natural
infectious agent or a recombinant agent expressing a foreign gene.
Antibody to the surface protein of virus particles that renders the virion noninfectious.
Seropositive versus Seronegative
Presence of antibody to a speci±c pathogen in the serum due to past infection or
immunization (seropositive) versus lack of antibody to a speci±c pathogen in the
serum because of no past infection or immunization.
Structural versus Nonstructural Protein
Viral protein species present in the virion (structural) versus viral protein species
synthesized in a virus-infected cell but not incorporated into the virion, such as viral
DNA polymerase of herpesviruses.
Puri±ed component of an infectious agent that is incapable of replication in the host
but can stimulate a protective immune response; for viruses, natural or