98
Combinatorial Phage Antibody Libraries
rearrangement to a conformation having fea-
tures in common with the infectious form,
EMBO J.
20
, 1554–1574.
Li, J., Pereira, S., Van Belle, P., Tsui, P., Elder,
D
.
,Sp
e
i
ch
e
r
,D
.
,D
e
en
,K
.
,L
inn
enb
a
ch
,A
.
,
Somasundaram, R., Swoboda, R., Herlyn, D.
(2001) Isolation of the melanoma-associated
antigen p23 using antibody phage display,
J.
Immunol.
166
, 432–438.
Liu, B.,
Marks, J.D.
(2000)
Applying
phage
antibodies to proteomics: selecting single
chain Fv antibodies to antigens blotted on
nitrocellulose,
Anal. Biochem.
286
, 119–128.
Marks, J.D., Hoogenboom, H.R., Bonnert, T.P.,
McCafferty, J., Grif±ths, D., Winter, G. (1991)
By-passing immunization. Human antibodies
from V-gene libraries displayed on phage,
J.
Mol. Biol.
222
, 581–597.
Maruyama, T.,
Rodriguez, L.L.,
Jahrling, P.B.,
Sanchez,
A.,
Khan,
A.S.,
Nichol,
S.T.,
Peters, C.J.,
Parren, P.W.H.I., Burton,
D.R.
(1999)
Ebola
virus
can
be
effectively
neutralized by antibody produced in natural
human infection,
J. Virol.
73
, 6024–6030.
Moulard, M., Phogat, S.K., Shu, Y., Labrijn, A.F.,
Xiao, X., Binley, J.M., Zhang, M.Y., Sidorov,
I.A., Broder, C.C., Robinson, J., Parren, P.W.
H.I., Burton, D.R., Dimitrov, D.S. (2002) Bro-
adly cross-reactive HIV-1-neutralizing human
monoclonal Fab selected for binding to gp120-
CD4-CCR5 complexes,
Proc. Natl. Acad. Sci.
U.S.A.
99
, 6913–6918.
Mullinax, R.L., Gross, E.A., Amberg, J.F., Hay,
B.N.,
Hogrefe, H.H.,
Kubitz, M.M.,
Gree-
ner, A., Alting-Mees, M., Ardourel, D., Short,
J.M., Sorge, J.A., Shopes, B. (1990) Identi±-
cation of human antibody fragment clones
speci±c for tetanus toxoid in a bacteriophage
lambda immunoexpression library,
Proc. Natl.
Acad.Sci.U.S.A.
87
, 8095–8099.
Mullis, K.,
Faloona, F.,
Scharf, S.,
Saiki, R.,
Horn, G., Erlich, H. (1986) Speci±c enzymatic
ampli±cation of DNA in vitro: the polymerase
chain reaction,
Cold. Spring. Harb. Symp.
Quant. Biol.
51
, 263–273.
O’Connell, D., Becerril, B., Roy-Burman, A.,
Daws, M., Marks, J.D. (2002) Phage versus
phagemid libraries for generation of human
monoclonal antibodies,
J. Mol.
Biol.
321
,
49–56.
Orlandi, R.,
Gussow, D.H.,
Jones, P.T.,
Win-
ter, G. (1989) Cloning immunoglobulin vari-
able domains for expression by the polymerase
chain reaction,
Proc. Natl. Acad. Sci. U.S.A.
86
,
3833–3837.
Parren, P.W.H.I.,
Marx, P.A.,
Hessell, A.J.,
Luckay, A.,
Harouse, J.,
Cheng-Mayer, C.,
Moore, J.P., Burton, D.R. (2001) Antibody
protects macaques against vaginal challenge
with
a
pathogenic
R5
simian/human
immunode±ciency virus at serum levels giving
complete neutralization in vitro,
J. Virol.
75
,
8340–8347.
Peretz, D., Williamson, R.A., Kaneko, K., Ver-
gara, J., Leclerc, E., Schmitt-Ulms, G., Mehl-
horn, I.R.,
Legname,
G.,
Wormald,
M.R.,
Rudd, P.M., Dwek, R.A., Burton, D.R., Prusi-
ner, S.B. (2001) Antibodies inhibit prion prop-
agation and clear cell cultures of prion infec-
tivity,
Nature
412
, 739–743.
Persson, M.A., Caothien, R.H., Burton, D.R.
(1991) Generation
of diverse high-af±nity
human monoclonal antibodies by repertoire
cloning,
Proc. Natl. Acad. Sci. U.S.A.
88
,
2432–2436.
Plotkin, S.A. (2001) Immunologic correlates of
protection induced by vaccination,
Pediatr.
Infect. Dis. J.
20
, 63–75.
Roovers, R.C., van der Linden, E., Zijlema, H., de
Bruine, A., Arends, J.W., Hoogenboom, H.R.
(2001) Evidence for a bias toward intracellular
antigens in the local humoral anti-tumor
immune
response
of
a
colorectal
cancer
patient revealed by phage display,
Int. J. Cancer
93
, 832–840.
Saphire, E.O., Parren, P.W.H.I., Pantophlet,
R., Zwick, M.B., Morris, G.M., Rudd, P.M.,
Dwek, R.A.,
Stan±eld, R.L.,
Burton, D.R.,
Wilson, I.A. (2001) Crystal structure of a
neutralizing human IGG against HIV-1: a
template for vaccine design,
Science
293
,
1155–1159.
Sastry, L., Alting-Mees, M., Huse, W.D., Short,
J.M., Sorge, J.A., Hay, B.N., Janda, K.D., Ben-
kovic, S.J., Lerner, R.A. (1989) Cloning of the
immunological repertoire in
Escherichia coli
for
generation of monoclonal catalytic antibodies:
construction of a heavy chain variable region-
speci±c cDNA library,
Proc. Natl. Acad. Sci.
U.S.A.
86
, 5728–5732.
Sblattero, D.,
Bradbury, A.
(2000)
Exploiting
recombination in single bacteria to make large
phage antibody libraries,
Nat. Biotechnol.
18
,
75–80.
Sheets, M.D., Amersdorfer, P., Finnern, R., Sar-
gent, P., Lindqvist, E., Schier, R., Heming-
sen, G., Wong, C., Gerhart, J.C., Marks, J.D.
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