132
Alternatively Spliced Genes
Tab. 1
Proteins detected in human spliceosomes.
Acce.#
Protein name
Yeast homolog
(SGD ORF)
Motifs
Cal. MWt
A. snRNP proteins
Sm/LSm core proteins
P14678
Sm B/B’
SMB1 (YER029C)
Sm 1 and 2
24 610
P13641
Sm D1
SMD1 (YGR074W)
Sm 1 and 2
13 282
P43330
Sm D2
SMD2 (YLR275W)
Sm 1 and 2
13 527
P43331
Sm D3
SMD3 (YLR147C)
Sm 1 and 2
13 916
P08578
Sm E
SME1 (YOR159C)
Sm 1 and 2
10 804
Q15356
Sm F
SMX3 (YPR182W)
Sm 1 and 2
9725
Q15357
Sm G
SMX2 (YFL017W-A)
Sm 1 and 2
8496
Q9Y333
hLSm2
LSM2 (YBL026W)
Sm 1 and 2
10 835
Q9Y4Z1
hLSm3
LSM3 (YLR438C-A)
Sm 1 and 2
11 714
Q9Y4Z0
hLSm4
LSM4 (YER112W)
Sm 1 and 2
15 350
Q9Y4Y8
hLSm6
LSM6 (YDR378C)
Sm 1 and 2
9128
Q9UK45
hLSm7
LSM7 (YNL147W)
Sm 1 and 2
11 602
U1snRNP-specifc proteins
P08621
U1-70kD
SNP1 (YIL061C)
RS, 1 RRM
70 081
P09012
U1 A
MUD1 (YBR119W)
2 RRMs
31 280
P09234
U1 C
YHC1 (YLR298C)
ZF
17 394
AB034205
LUC7A
LUC7 (YDL087C)
RS-rich
51 466
U2snRNP-specifc proteins
AF054284
SAP155 (SF3b155)
HSH155 (YMR288W)
PP2A
1 45 815
Q13435
SAP145 (SF3b145)
CUS1 (YMR240C)
Pro-rich
97 657
AJ001443
SAP130 (SF3b130)
RSE1 (YML049C)
1 35 592
Q15459
SAP114 (SF3a120)
PRP21 (YJL203W)
SWAP, UBQ
88 886
Q15428
SAP62 (SF3a66)
PRP11 (YDL043C)
ZF
49 196
A55749
SAP61(SF3a60)
PRP9 (YDL030W)
ZF
58 849
Q15427
SAP49 (SF3b49)
HSH49 (YOR319W)
2 RRMs
44 386
P09661
U2 A
0
LEA1 (YPL213W)
Leu-rich
28 444
P08579
U2 B
00
MSL1 (YIR009W)
2 RRMs
25 486
Q9Y3B4
p14
SNU17 (YIR005W)
1 RRM
14 584
U5snRNP-specifc proteins
AB007510
U5-220kD (PRPC8)
PRP8 (YHR165C)
2 73 785
O75643
U5-200kD
BRR2 (YER172C)
DExD, Helicase
1 94 479
BC002360
U5-116kD
SNU114 (YKL173W)
G domain
1 09 478
BC001666
U5-102kD
PRP6 (YBR055C)
HAT
1 06 925
BC002366
U5-100kD
PRP28 (YDR243C)
DExD, Helicase, RS
95 583
BC000495
U5-52kD
SNU40 (YHR156C)
GYF
37 646
AF090988
U5-40kD
WD40s
39 299
O14834
U5-15kD
DIB1 (YPR082C)
16 786
U4/U6snRNP-specifc proteins
T50839
U4/U6-90kD
(HPRP3)
PRP3 (YDR473C)
PWI
77 529
BC007424
U4/U6-60kD
(HPRP4)
PRP4 (YPR178W)
WD40s
58 321
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