Chirality in Biology
Books and Reviews
Describing an object or a molecule whose image in a plane mirror cannot be
superposed on the original.
A pharmaceutical agent that exists in two enantiomeric forms. In many cases, the two
forms will have different physiological activity.
A methyl group with the three hydrogen isotopes,
H. When combined with
another group, R, a chiral molecule is obtained: R-C
Chiral Phosphorous Atom
A phosphorous atom linked to the three oxygen isotopes,
O, and to another
group, usually OR: hence, RO–P–
Discrimination between enantiomers achieved by enzymes or biological receptor
molecules and by some chemical catalysts and reagents.
Three-dimensional arrangement of atoms or groups of atoms at an element of
chirality; arrangements resulting from rotation about single bonds are excluded.
Stereoisomers not in an object-/mirror-image relationship.
An arbitrary convention to denote conFguration about a chiral element in
-hydroxy acids, and carbohydrates.
Stereoisomers that are in an object-/mirror-image relationship.
sense. Normal protein amino acids have L-conFguration; for naturally occurring
carbohydrates, the D-conFguration predominates. The antonym is heterochiral.