Chicken Genome
541
ADL0247
LEI0882
ADL0247
LEI0082
TH
MCW0038
MCW0038
ROSO110
INS INS
TH
TGFB3-TCFB3
LEI0145
MCW0032
MCW0029
ADL0187
MCW0081
ADL0166
ADL0298
ROS0110
TCFB3
MCW0078
MCW0029
MCW0032
ADL0166
ADL0298
MCW0081
ADL0187
ADL0312
LEI0145
MCW0078
ADL0312
ADL0292
ADL0292
ROS0013
ROS0013
0
20
40
60
80
100
120
140
160
0
10
20
30
40
50
60
70
80
90
100
110
120
130
140
150
160
170
180
190
Chicken
5
Chicken
5
Chicken
5
194.62 cM
170.30 cM
Averaged
male
female
Averaged
male
female
p1.1
A1.1
A1.2
A1.3
A1.4
A2.1
A2.2
A2.3
A2.4
A2.5
A2.6
A2.7
Wageningen
East Lansing
Cytogenetic
Fig. 2
Integration of genetic and physical maps of chromosome 5 (Arkdb-CHICK, June 2003).
has been a fast and simple method of
mapping genes in recent years. The def-
inition of a standard karyotype for the
chicken by Ladjali-Mohammedi et al. has
helped to exchange and compare data
between different laboratories, in partic-
ular, for the larger chromosomes 1 to
8 and the sex chromosomes Z and W.
Recent developments in the isolation of
BAC clones and the isolation of indi-
vidual microchromosomes have increased
the possibility of a universal set of DNA
or ‘‘Landmark probes’’ speciFc to each
chromosome, including all 30 microchro-
mosomes. In ±ig. 3, chromosome paints
derived from isolated chicken chromo-
somes have been used to identify homolo-
gous chromosomes in the turkey genome.
To date, 218 genes have been assigned
by ±ISH to a speciFc chromosome and
37 genes have been mapped to nonspe-
ciFc microchromosomes. Through these
experiments, genetic linkage maps have
been assigned to speciFc chromosomes
(e.g. ±ig. 2 shows an integrated view of
chromosome 5).
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