429
Cell Signaling During Primitive
Hematopoiesis
Devorah C. Goldman and Jan L. Christian
Oregon Health and Science University, Portland, OR, USA
1
Primitive Hematopoiesis
430
2
Specifcation, Expansion and DiFFerentiation oF the Primitive Erythroid
Lineage
435
2.1
The Signal to become Ventral
436
2.2
Specifying Primitive Hematopoietic Cell Fate
436
2.3
Regulating the Production, Expansion and Survival of Primitive
Erythroid Progenitors
437
3
Role oF Cell–Cell Interactions in Primitive Hematopoiesis
442
3.1
Extraembryonic Endoderm
442
3.2
Ectoderm
443
3.3
Endothelial Cells
443
3.4
Role of the Microenvironment in Regulating Primitive
and De±nitive Potential
444
4
Summary and Perspectives
444
Bibliography
445
Books and Reviews
445
Primary Literature
445
Keywords
Hematopoietic Stem Cell (HSC)
A pluripotent cell that gives rise to all of the blood lineages and has the ability to
undergo self-renewal.
Encyclopedia of Molecular Cell Biology and Molecular Medicine, 2nd Edition
. Edited by Robert A. Meyers.
Copyright
2004 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
ISBN: 3-527-30544-0
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